此前,来自 多伦多大学的研究团队 却颠覆性地发现, 常见益生菌之一的乳杆菌能将膳食中的色氨酸代谢为吲哚,增加肿瘤相关巨噬细胞的活性,从而抑制肿瘤免疫,促进胰腺导管腺肿瘤的生长。 该研究发表在Cell子刊 Immunity 上。
IL-17A may exert its anti-LUAD effects through extensive interactions with genes related to ferulic acid 4-sulfate metabolism (such as SULT1A1, CYP1A1, etc.), inhibiting oxidative stress and ...
1 Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, United States 2 Department of Medicine, Michigan State University, East Lansing, MI, United States Tumor ...
研究发现,士的宁的毒性是马钱子碱的10倍以上。CYP450酶系中的多种代谢酶如CYP1A1、CYP2C9和CYP3A4等均参与士的宁的代谢,其中CYP3A4酶催化氮氧化反应,生成的代谢产物士的宁氮氧化物毒性较小且具有良好的生物活性。斑马鱼的代谢组学研究表明,马钱子的肝毒性 ...
The full CMI on the next page has more details. If you are worried about using this medicine, speak to your doctor or pharmacist. 1. Why am I taking APO-IRBESARTAN HCTZ? APO-IRBESARTAN HCTZ contains ...