回首抗磷脂抗体领域的检验发展之路，其最初建立于1983年，选用的是放射免疫法（radioimmunoassay，RIA）[1]，后被更为安全的酶联免疫分析法（enzyme-labled ...

▎药明康德内容团队编辑根据PDUFA的预期目标日期，预计2025年1月，美国FDA将对3款创新药物的批准做出监管决定，本文将对这些疗法进行相关介绍。▲2025年1月有望在美国获批的新药（药明康德内容团队制图，点击可见大图）活性成分：Tabelecle ...

This important work substantially advances our understanding of reactive oxygen species (ROS) as a regenerative signal during postnatal cerebellum repair by activating adaptive progenitor ...

Results ANA Speckled pattern is associated with mild to moderate disease (P=0.02). Most frequent antibodies are anti-dsDNA (63%), SSA (24%) and Ku (17.5%). Anti-cardiolipin (aCL) antibodies are ...

001). Median progression free survival was 6.9 months in the Dato-DXd arm and 4.9 months in the chemotherapy arm. Barth syndrome is caused by a mutation in the tafazzin gene, which results in reduced ...

▎药明康德内容团队编辑前不久，行业知名机构CPHI（世界原料药博览会）在280名全球产业高管中开展的调研结果显示，在当前极具吸引力、值得关注的治疗模式中，核酸和多肽（TIDES）疗法以43%的得票率位列第二，仅次于生物制品（53%）。TIDES疗法不 ...

Department of Chemistry and Sarafan ChEM-H Institute, Stanford University, Stanford, California 94305, United States Department of Microbiology and Immunology, Stanford School of Medicine, Stanford, ...

而存在于线粒体内膜上ATP合酶（又称为F0F1-ATP酶），则是线粒体内最重要的负责生成ATP的分子机器。此外，一种富含于心脏细胞线粒体内膜中的心磷脂（cardiolipin）对能量产生有着极其重要的作用。在几种遗传性心脏疾病如Barth综合征、Sengers综合征、扩张型共济 ...

A systematic literature search for clinical reports and reviews published between 2000 and 2008 was undertaken using Pub Med and the Cochrane databases. Search words were "HELLP syndrome", and ...

Department of Physics, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University (UNESP), São José do Rio Preto, 15054-000 São Paulo, Brazil ...