Drugs acting on the cholinergic system can improve or worsen cognitive abilities, and their effects are particularly pronounced in frail elderly individuals and patients with Alzheimer disease.

Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic drugs in chronic asthma management has been largely underestimated. Several ...

Such studies have resulted in the discovery of an association between a decline in learning and memory, and a deficit in excitatory amino acid (EAA) neurotransmission, together with important roles ...

The importance of the brain renin-angiotensin system in cardiovascular function is well accepted. However, not knowing the precise source of renin in the brain has been a limitation toward a complete ...

In Alzheimer’s disease (AD) there’s a significant atrophy of the basal forebrain cholinergic neurons and losses of synaptic terminations in the cerebral cortex and hippocampus. These neurons depend on ...

Summary: Alcohol use disorder (AUD) disrupts cognitive flexibility, crucial for learning and adapting to change. New research ...

Discover groundbreaking research on how chronic alcohol use affects cognitive flexibility and brain signaling circuits, ...

Alcohol use disorder (AUD) affects about 400 million people worldwide and is a leading cause of serious illnesses such as ...

Dec. 18, 2024 — Dancing lowers the depression associated with Parkinson's disease, and the benefits can be seen in multiple ways, a new study ...

Texas A&M researchers found that chronic alcohol use disrupts cholinergic interneuron (CIN) firing patterns in the brain, ...

Dec. 19, 2024 — Scientists have unveiled groundbreaking research on the origins of lunar water, offering insights that could reshape our understanding of the Earth-Moon system and the broader ...