Here we investigate the fate of single secretory vesicles after fusion with the plasma membrane by measuring capacitance changes and transmitter release in rat chromaffin cells using the cell ...

Serotonin is produced peripherally by the intestinal chromaffin cells and centrally by nuclei found in the lower pons and upper brain stem (Mills, 1997). It regulates emotional, personality ...

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

Phaeochromocytomas are rare catecholamine-secreting tumours, usually benign, originating from chromaffin cells of the adrenal glands. Their typical presentation includes the triad of headaches, ...

Dec. 17, 2024 — Researchers developed a fully open-source biomolecular structure prediction model that achieves state-of-the-art performance, at the level of ...

The 2004 WHO classification of endocrine tumors defines pheochromocytoma as a tumor arising from catecholamine-producing chromaffin cells in the adrenal medulla -- an intra-adrenal paraganglioma.

Stem cells are cells that have the capacity to self-renew by dividing and to develop into more mature, specialised cells. Stem cells can be unipotent, multipotent, pluripotent or totipotent ...

This fundamental work substantially advances our understanding of the role of calcium-binding proteins 1 and 2 (CaBP1 and CaBP2) for generating sustained calcium currents in mouse inner hair cells and ...

CD4 T helper cells are a type of white blood cell called a lymphocyte that serves an important role in your immune system. These cells help defend the body against infection by directing other "killer ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Researchers are exploring the world’s first virtual human cell, an AI-powered model designed to simulate the complex behavior of human biomolecules, cells, and tissues. Credit: Emma Lundberg Recent ...

NIH-funded mouse study provides roadmap for how aging may alter brain cell genetic activity Based on new brain mapping research funded by the National Institutes of Health (NIH), scientists have ...