You will be redirected to our submission process. Recent years have seen rapid progress in our understanding of the structure and function of eukaryotic chromosomes- the mechanisms by which they are ...

Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...

So, this whole idea of chromatin packing and chromatin folding comes into play, of where are the genes in the cell, and how are they regulated that way,” remarked Cosgrove. “Generally, methylation at ...

You can either spend hours editing your packing list, try method upon method to cram more into your bags or you can invest in a set of compression packing cubes. If saving space and staying more ...

Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell ...

We show that TPR is required for the activation of innate immune signalling at these early stages of senescence and we link this to the formation of heterochromatin-enriched cytoplasmic chromatin ...

A $4.75m grant will support the development of EIS-12656, which is being studied alone and in combination with PARP inhibitors.

Cancer is a disease driven by progressive genetic and epigenetic aberrations that manifest as global alterations in chromatin packaging and by specific promoter changes that influence the ...

This manuscript provides valuable information about the genesis of CPSF6 condensates due to HIV-1 infection. However, the evidence is incomplete as it is missing more functional assays. Furthermore, ...