Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking ...

Research conducted at the Department of Biology, University of Padova, has identified critical genomic milestones in the ...

All array platforms will detect copy number variations including deletions, duplications, unbalanced translocations, some marker chromosomes and aneuploidy. SNP arrays have the added advantage of ...

In particular, this work is aimed at allowing the many chromosomal translocation proteins, found in all cancers from leukaemia/lymphoma, sarcomas and carcinomas, to be used as drug targets in cancer ...

Background The potency of T cell-mediated responses is a determinant of immunotherapy effectiveness in treating malignancies; however, the clinical efficacy of T-cell therapies has been limited in ...

Courtesy of Greenwood Genetic Center. Segregation of a Robertsonian translocation: During this process, the short arms of 2 chromosomes are lost. The long arms fuse together at the centromere.

Sometimes though, Wolf-Hirschhorn syndrome is caused when one of the parents has something called a “balanced translocation.” That means two or more of their chromosomes broke and switched ...

Chromosome abnormality is the condition in a cell or organism where the number of chromosomes or the structure of any chromosome differs from the normal karyotype. When the variant genotype is not ...

We Homo sapiens possess surprisingly few functional genes that distinguish us from extinct human lineages such as ...

During a Case-Based Roundtable® event, Daniel A. Ermann, MD, discussed evaluation and treatment for a patient with relapsed ...

Researchers' initial understanding of meiosis was based upon careful observations of chromosome behavior using light microscopes. Then, in the 1950s, electron microscopy provided scientists with a ...

Department of Medical Genetics, University of Alberta, Edmonton, Alberta T6G 2H7, Canada Correspondence to: Dr D W Cox, 8-39 Medical Sciences Building, University of Alberta Edmonton, Alberta T6G 2H7, ...