We have previously reported that cultures of C. albicans activated the amebocyte lysate clotting cascade of the Japanese horseshoe crab Tachypleus tridentatus. In order to isolate the active agent ...
The top panel, designed with BioRender.com, illustrates the process of clot formation and lysis, beginning with platelet aggregation and activation of the coagulation cascade, followed by the ...
See Figure 1 for a depiction of normal hemostasis. The activation of the coagulation cascade yields thrombin that converts fibrinogen to fibrin; the stable fibrin clot being the final product of ...
interacts with coagulation factor VIIa to initiate the plasma coagulation cascade. The TF and factor VIIa complex triggers the activation of other clotting factors, which leads to the formation of ...