近年来,抗逆转录病毒疗法(ART)在抑制HIV复制方面取得了显著进展,显著延长了艾滋病患者的寿命,但该疗法同时也带来了严重的副作用,并导致大量耐药病例的出现。CD4作为HIV进入宿主细胞的主要受体,一直是HIV药物研发的重点靶点。然而,目前唯一的CD4抗体药物在抑制HIV病毒的广谱性和效率上仍存在不足,长期应用会导致耐 ...
Eyelids not in normal contact with the eyeball, they are turned inwards or outwards Signs of dermatitis irritation in skin folds, and/or hair loss or scarring from previous dermatitis Incorrect hind ...
Particular points of concern for individual breeds may include features not specifically highlighted in the breed standard including current issues. In some breeds, features may be listed which, if ...