Introduction: Dengue viruses (DENVs), the causative agents of dengue hemorrhagic fever and dengue shock syndrome, undergo genetic mutations that result in new strains and lead to ongoing global ...

No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...

The NS5-B quadruplex sequence, which is located in the genome region encoding the methyltransferase domain of the viral polymerase, was selected for this study based on previous biophysical ...

Dengue is a miserable illness caused by infection with any of the four dengue viruses (dengue-1, -2, -3 and -4). Infections have increased dramatically over the past two years while, at the same ...

Scientists have has pioneered antivirals targeting viral methyltransferases, offering a new strategy for treating RNA and DNA ...

In fact, a new study by the Tuschl laboratory introduces a proof-of-concept for a novel class of antivirals that would target a type of enzyme essential not just to SARS, but also many RNA viruses, ...

Dengue fever is a common tropical infection. This acute febrile illness can be a deadly infection in cases of severe manifestation, causing dengue hemorrhagic shock. In this brief article, I will ...

After consulting with doctors in the Boston area, he learned that he had dengue fever. The diagnosis shocked Korb, my 47-year-old cousin, who frequently travels to tropical destinations.

FILE - Jenny Chiroque sits on a bed with netting at La Merced Hospital where she is treated for dengue in Paita, Peru, Feb. 29, 2024. (AP Photo/Martin Mejia, File) SAN JUAN, Puerto Rico (AP ...

but also many RNA viruses, including Ebola and dengue, as well as cytosolic-replicating DNA viruses, including Pox viruses. The findings may pave the way for a faster and more robust response to ...

MEXICO CITY (Reuters) - Reported cases of dengue in the Americas nearly tripled to a record high of over 12.6 million this year, including 21,000 severe cases and over 7,700 deaths, the Pan ...