This paper presents the important discovery that lipid metabolic imbalance caused by Snail, an EMT-related transcription factor, contributes to the acquisition of chemoresistance in cancer cells.

Pharmacogenomics targets resistance mechanisms (efflux pumps, ribosome). Pharmacogenomics boosts new strategies (elicit dormant bacteria, immune response).

This important study will allow for a better understanding of anthelmintic drug resistance in nematodes, a growing concern for public health. The authors provide a detailed analysis of the role of UBR ...

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These MDR proteins lead to the production of drug efflux pumps, which actively transport taxanes and other drugs out of cancer cells. This prevents the accumulation of therapeutic intracellular ...

Scientists find a vulnerability in antibiotic resistance mechanism Date: December 17, 2024 Source: Technische Universität Dresden Summary: Superbugs, bacteria that are immune to multiple ...

Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, KY, United States Figure 2. Bacillales phylogenetic relationships ...

ABSTRACT: Background: Surgical sponges are used in almost all surgeries in Liberia and around the world. They sometimes may inadvertently be left in the body following a surgery and are then referred ...

Research Unit of Structural Chemistry & Computational Biophysics, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin 13125, Germany ...