2009 Mineralo–protein complexes containing fetuin-A and albumin form through a dual inhibition–seeding mechanism in human body fluids [34] Mahamid et al. 2010 Amorphous calcium phosphate ...
After studying the axolotl for 8 years, researchers are developing a line of cosmeceutical and over-the-counter products ...
2024年12月5日,上海交通大学医学院洪登礼团队在 Nature 期刊发表了题为:Fetal hepatocytes protect the HSPC genome via fetuin-A 的研究论文。 该研究以胚胎造血发育为模型,揭示了胚胎发育组织维持干细胞基因组稳定性及胚胎发育相关疾病起源的机制。 研究团队先建立肝 ...
系列实验表明,肝细胞通过分泌胎球蛋白A(Fetuin-A)保护HSPCs的基因组。Fetuin-A可结合HSPCs表面的TLR4受体,激活TLR4-MYD88-bZIP通路,上调核酸解旋酶BLM的 ...
Osteoporosis (OP) stands as the most prevalent systemic skeletal condition associated with aging. The current clinical management of OP predominantly depends on anti-resorptive and anabolic agents.
Haematopoiesis refers to the commitment and differentiation processes that lead to the formation of all blood cells from haematopoietic stem cells. In adults, haematopoiesis occurs mainly in the ...
Objective Gestational diabetes mellitus (GDM) is a metabolic disorder associated with adverse maternal and neonatal outcomes. While GDM is diagnosed by oral glucose tolerance testing between 24–28 ...
Objective: To investigate the ability of the estimated plasma gene-expression levels of microRNA (miR)-21 and 126 to define patients suspected to have hepatocellular carcinoma (HCC) among patients ...