Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking ...

Research conducted at the Department of Biology, University of Padova, has identified critical genomic milestones in the ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Two tigresses brought from Maharashtra to Similipal Tiger Reserve are in good health. One ventured into West Bengal but is monitored and efforts are underway to guide her back. The translocation aims ...

The University of Cape Town, along with the Giraffe Conservation Foundation, have conducted a large-scale study identifying ...

In some cases, parts of two chromosomes may be interchanged (translocation). It is usually (but not always) a combination of mutations in oncogenes and tumor suppressor genes that leads to the ...

Genome analysis of New Zealand’s forest parrot kākā has so far found no genetic differences between its two subspecies. This ...

detection of gene disruptions becomes possible. Microarray result of an apparently balanced translocation t(5;19)(q11.2;q13.1) by karyotyping showing no gain or loss at the translocation breakpoints.

Objective Here, we aimed to investigate the key genes contributing to immune escape in HCC and raise a new therapeutic strategy for remoulding the HCC microenvironment. Design The genome-wide in vivo ...

When the chromosomal translocation occurs, a piece of chromosome 11 moves next to the EWSR1 gene on chromosome 22. This causes the EWSR1 gene to be activated constantly, resulting in cell ...

A well established mechanism for genetic alterations in haematopoietic malignancies involves the translocation of genetic material from one chromosome to another, resulting in the dysregulation of ...

Dec. 19, 2024 — When introducing genes into yeast to make it produce drugs and other useful substances, it is also necessary to reliably switch the production on or off. Researchers have found ...