Glial cells come in many forms, but three major types are currently recognized: astrocytes, oligodendrocytes and microglia. The first are primarily involved in creating the blood-brain barrier and ...

Microglia are the brain's resident immune cells. Their job is to patrol the brain's blood vessels looking for invading ...

A review of the recent evidence suggests that GLP-1 drugs, such as semaglutide, could protect brain health and cognitive ...

The Deneen Lab seeks to unlock the enigmatic biology surrounding glial cell development and function in the brain. Beginning with developmental gliogenesis, we identified the key transcriptional ...

By Tarun Sai Lomte New insights into brain development: study maps chromatin changes linked to psychiatric disorders in ...

Research highlights how GLP-1 receptor agonists may improve brain health by targeting the neurovascular unit, linking ...

Our laboratory sits at the interface between stem cell biology and developmental neuroscience. We use pluripotent stem cells to model neurological development and disease with a specific focus on ...

For human tissues, prior experimental manipulations are impractical, and genomic alterations are employed. Somatic mutations mark subclones and their fates can be reconstructed with DNA sequencing ...

It's never too early—or too late—to safeguard your mind against age-related decline. Here's what you can start doing today.

Michael Barresi’s research interests are focused on how glial cells help wire the nervous system in the embryonic zebrafish brain. His lab discovered that astroglial cells provide a substrate for ...