Abnormalities are not generally detected on digital rectal examination in patients with HGPIN, possibly making it indistinguishable from cancer on imaging, manifesting as a hypoechoic lesion on ...
2007;4(6):321-332. Blockade of 5α-reductase with drugs such as finasteride does not seem to induce large morphological changes in HGPIN, unlike other forms of androgen deprivation therapy.
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