a method where athletes live at or near sea level but train under hypoxic conditions, has gained unprecedented popularity. By adding the stress of hypoxia during ‘aerobic’ or ‘anaerobic’ interval ...

One such pathway, the hypoxic response pathway, is activated by reduced local oxygen concentrations at the tumor site. Hypoxia-driven gene and protein changes enhance epithelial-to-mesenchymal ...

Third, the development of new hypoxic devices (eg, mobile inflatable hypoxic marquees) and methods (repeated sprints in hypoxia). This increased interest was translated by the organisation of ...

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their ...

Researchers identify key regulator that induces cancer-killing capacity in T cells under hypoxia: Birmingham, Alabama Monday, December 16, 2024, 17:00 Hrs [IST] Immune checkpoint ...

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their ...

The UAB researchers found that HIF1α-glycolysis is indispensable for IFN-γ induction in hypoxic T cells. HIF1α is a subunit of HIF, or hypoxia-inducible factor, that is known to play a crucial ...

At this point, descent to lower altitude or treatment in a (portable) pressure chamber and administration of oxygen are critical to prevent hypoxia and life-threatening high-altitude hypoxic brain ...

“However, it has been unknown, under hypoxia, whether and how HIF1α regulates IFN-γ induction and glycolysis in T cells.” The UAB researchers found that HIF1α-glycolysis is indispensable for IFN-γ ...

At this point, descent to lower altitude or treatment in a portable pressure chamber and administration of oxygen are critical to prevent hypoxia and life-threatening high-altitude hypoxic brain ...