Objectives The circadian clocks are internal timing mechanisms that drive ∼24-hour rhythms in a tissue-specific manner. Many aspects of the physiology of the intervertebral disc (IVD) show clear ...
Objectives: We conducted this systematic review of animal models of paraspinal muscle (PSM) degeneration secondary to degenerative intervertebral disc (IVD), providing a comprehensive evaluation of ...
This important study demonstrates the therapeutic potential of recombinant human PDGF-AB/BB proteins in reducing the senescent signatures of primary human intervertebral disc cells. The study ...
Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, No. 37, Guoxue Road, Chengdu 610041, China ...