Negative-pressure pulmonary edema (NPPE) occurs when a large, negative intrathoracic pressure is generated against an obstructed upper airway, causing fluid to shift into the lung interstitium.

Many people dismiss straining during bowel movements as a minor inconvenience, but this habit can lead to serious health complications. Regular diffic ...

Intrathoracic obstruction is most severe during ... is increased during inspiration because of the effect of atmospheric pressure to compress the trachea below the site of obstruction.

However, because of the changes in venous tone, intrathoracic pressures (positive end expiratory pressure, etc.), left and right ventricular compliance and geometry that occur in critically ill ...