Malignant cells down-regulate cell death by overexpressing a transcription factor called BCL6. “Our idea was to borrow a little bit of the activity of the kinase and drag it over to where BCL6 is ...
在这项研究中,研究人员报道了铜绿假单胞菌中的丝状温和噬菌体携带的三组分毒素-抗毒素系统KKP(kinase-kinase-phosphatase)的双重功能。原噬菌体诱导通常通过控制噬菌体阻遏蛋白活性进行调节,例如宿主因子对阻遏蛋白的特异性切割使其失 ...
Oncodesign Precision Medicine (OPM) (ISIN: FR001400CM63; Mnemonic: ALOPM), a biopharmaceutical company specializing in ...
The most difficult subtype of breast cancer to treat is triple-negative breast cancer (TNBC). Over 20,000 cases of TNBC are ...
Tuesday announced positive topline data from the Phase 3 MINT study evaluating Uplizna for the treatment of adults ...
BeiGene, Ltd. (NASDAQ: BGNE; HKEX: 06160; SSE: 688235), a global oncology company, today announced it will share research from studies evaluating BRUKINSA® (zanubrutinib), Bruton tyrosine kinase (BTK) ...
洛拉替尼助力患者走向临床治愈:对于ALK阳性晚期NSCLC一线治疗,临床医生应基于国内外权威指南,综合考量药物的疗效和安全性,以及患者的疾病特征、ECOG PS评分、患者意愿和家庭经济条件等因素,做出恰当的选择。洛拉替尼具有独特大环结构,更容易穿透血脑屏障,可广泛覆盖、强效抑制ALK已知耐药突变,在CROWN研究中获得目前最长研究者(INV)评估mPFS(95% ...
Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to ...
Biotechnology Co. Ltd. has disclosed proteolysis targeting chimeras (PROTACs) comprising a cereblon (CRBN) ligand coupled to a mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1; HPK1; ...