The “bottleneck” of current gene therapy approaches is the lack of an efficient gene delivery system. Retroviral vectors have been very useful for ex vivo gene delivery, but suffer two major ...
1996a) (Naldini et al., 1996b) , the vector pCMVΔR8.2 supplies all but the HIV envelope in trans, the vector pMD.G is used to produce the VSV-G pseudotype, while the transgene (lac Z) is inserted into ...
Discover Lyell Immunopharma's groundbreaking patent for EGFR-derived polypeptides, enhancing cancer treatment through innovative nucleic acid technologies and engineered T cells.
Discover how Oxford BioMedica's new patent enhances viral vector production efficiency with a novel nucleic acid sequence that regulates therapeutic protein translation.
Following a comprehensive review of its operations, bluebird bio, Inc. (Nasdaq: BLUE) today announced that the Company is implementing a restructuring intended to optimize the Company’s cost structure ...