Most patients received the recommended once daily dose of 80mg valsartan or valsartan/HCTZ 80/12.5mg. On the basis of about 20 000 patient-years, the number of deaths observed in the studies (22 ...
Bolland and colleagues previously conducted a 2-year controlled, blind study in postmenopausal women who received hydrochlorothiazide 50 mg daily or placebo. There were significant, sustained ...
In trial 2, 75.8% of patients received valsartan/HCTZ alone over the complete study period. The changes in systolic (SBP) and diastolic (DBP) blood pressure are presented in table II and figure 1.
Soon after, other combinations were being tested in the clinic, such as ACE inhibitors and diurectics (lisinopril and hydrochlorothiazide); ARBs and diuretics (losartan or valsartan and ...
USA: A recent secondary analysis of a randomized clinical trial compared chlorthalidone and hydrochlorothiazide to assess their effects on kidney outcomes in patients with hypertension. The findings, ...
including ACE inhibitors such as lisinopril (Zestril), beta-blockers such as propranolol (Inderal), diuretics such as furosemide (Lasix) and hydrochlorothiazide, and calcium-channel blockers such ...
25,26 Results were consistent for all outcomes by age, sex, diabetic status, and ethnicity, except for stroke and combined CVD. For these end points, significant heterogeneity was seen in the ...
Some blood pressure medications (antihypertensives) may cause weight gain, loss, or neither. The beta-blockers atenolol, metoprolol, and propranolol are commonly linked to weight gain. If you’re ...