The efficacy of nebivolol in treating hypertension has also been compared with HCTZ in a factorial design study, as seen in ( Figure 3). [62] After a 4-week placebo run-in period, patients were ...

USA: A recent secondary analysis of a randomized clinical trial compared chlorthalidone and hydrochlorothiazide to assess their effects on kidney outcomes in patients with hypertension. The findings, ...

In trial 2, 75.8% of patients received valsartan/HCTZ alone over the complete study period. The changes in systolic (SBP) and diastolic (DBP) blood pressure are presented in table II and figure 1.