Data sources Randomised controlled trials (RCTs) comparing high-intensity statin therapy (atorvastatin 80 mg or rosuvastatin 20/40 mg) with moderate/mild statin treatment or placebo were derived from ...

Compared with high-intensity statin therapy, moderate intensity statin therapy plus ezetimibe was equally effective in preventing CV events among patients undergoing PCI. Moderate-intensity statin ...

Medically reviewed by Femi Aremu, PharmD Zocor (simvastatin) and Lipitor (atorvastatin) are both statin drugs, which are ...

Because higher doses of a statin, and high intensity statins, reduce LDL cholesterol more, the hypothesis has been that they are better and should be used more liberally. Some treatment guidelines ...

A research team led by Hong Soon-joon, Cha Jung-joon, and Kim Joo-hyun of the Department of Circulatory Mechanics at Korea ...

Some research supports statin use for people with kidney disease or kidney failure and heart disease. Other research recommends caution for those with kidney issues. Heart disease is a major cause ...

"In fact, nearly two-thirds of patients on Repatha in this trial, the vast majority of whom were already on high to moderate intensity statin therapy at baseline, experienced a reduction in plaque ...

Current AHA guidelines call for healthy Americans to bring LDL below 100 milligrams per deciliter (mg/dL) of blood, while ...

Most statin drugs are FDA-approved for children and teens under age 18, but only if they have a genetic condition that cause extremely high levels of LDL (bad) cholesterol. Yet in 2009 ...

Use of statins was cost-effective with the cost per QALY gained below £3502 for standard therapy and below £11,778 for higher intensity therapy, which is well under the current threshold for ...