The discovery of histone lysine demethylases has provided the opportunity for a detailed exploration of the regulation of histone-methylation dynamics. Although the focus of the past few years has ...

Lysine is an essential amino acid found in both plant- and animal-based foods that are high in protein. Lysine supplements have been studied for potential health benefits, including cold sore ...

Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme encoded by EZH2 gene. EZH2 methylates non-histone proteins such as the transcription factor GATA4 and the nuclear ...

Histone Lysine N Methyltransferase is an enzyme that in humans is encoded by a gene EZH1 ... which means it helps control gene expression without altering the DNA sequence itself. The main role of ...

Chemical changes to histones, the proteins that help to pack and organize DNA inside cells, play a key role in determining ...

The sequencing of the human genome at the turn of the 21st century was heralded as a monumental scientific achievement ...

We propose that SDGs displace PRC2 from PREs, preventing the deposition of H3K27me3 and activating the expression of target genes through transcription-coupled H3K36 methylation. Here we identify SDG7 ...

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the ...

However, it has shown limitations in terms of high costs and inefficiencies. The productivity and accuracy of DNA methylation detection rely critically on the optimization of methodologies and the ...