The endosomal and lysosomal membranes of cells that demonstrate high rates of lipid-trafficking are enriched with lysobisphosphatidic acid (LBPA), which is a potential target for the aPL antibodies.

that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The ...