Although these were hotly debated issues at the time, it is now clear that a multitude of signal transduction pathways and numerous regulatory mechanisms have evolved to keep MYC expression under ...

Vital research findings pointing to improved treatment for children with brain tumours have been revealed in two major ...

Vital research findings pointing to improved treatment for children with Group 3 medulloblastoma brain tumors have been ...

Researchers have identified a critical group of medulloblastoma, a form of brain cancer in children, which is near incurable ...

LINC00901 regulates MYC signaling pathway. (A) LINC00901 level is significantly associated with MAPK signaling pathway. Bulb map of KEGG pathway analysis of differentially expressed genes in MIA ...

By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found that activation of the MYC gene -; a well-known cancer-causing gene -; sets ...

A number of signaling pathways have been shown to be central to myeloma growth and survival including NFκB, MAPK, PI3K, JAK/STAT, MYC, MAF and the UPR. Molecules inhibiting these pathways have ...

“This is a very powerful oncogenic pathway set off by MYC activation,” says Srinivasan Yegnasubramanian, M.D., Ph.D., professor of oncology, pathology, and radiation oncology and molecular ...

The pathways diagram (Academic career pathway diagram (PDF, 89kB)) shows the three pathways and roles, including accepted progression and promotion routes.‌‌ The clinical career pathways are sub-sets, ...

For example, in plants, specific metabolic pathways can produce glucose and chlorophyll. Metabolic pathways can be described as a series of chemical reactions that start with a substrate and ...

Correction to: LINC01296/miR-26a/GALNT3 axis contributes to colorectal cancer progression by regulating O-glycosylated MUC1 via PI3K/AKT pathway. Correction to: Stemness marker ALDH1A1 promotes ...