It is hard to overestimate the importance of antibodies in the frameworks of biotechnology and pharmaceutical industries.

Here, the authors develop a compact system for simultaneous and independent gene editing, activation, and repression in mammalian cells ... critical insights into structure-activity relationships.

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

The two main types are the protein storage vacuoles of neutral pH, and the lytic vacuoles of acidic pH, which are equivalent in function to lysosomes in mammalian cells (Figure 1). A special ...

Stator assigns multiple states and (sub)types to a single cell using coordinated gene expression and/or non-expression in a ...

First, circulation and blood flow to our extremities can diminish or become impaired, meaning toenails could receive fewer ...

During the development of the olfactory epithelium (OE), olfactory sensory neurons (OSNs) express only one member of the odorant receptor (OR) gene family, and O ...

Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds. The disorders ...

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein ...

The COVID pandemic is ongoing, but scientists are on alert for any pathogen that might lead to another global outbreak of ...

自2018年成立以来，西湖大学吸引了许多国内外优秀的青年学者及知名科学家的加入，经过短短几年的发展，西湖大学建立了理学院、工学院、生命科学学院和医学院四大院系，并取得了一系列重要学术突破。 据《生物世界》 统计 ...

Yale researchers identified an underactive mTOR pathway as a cause of lissencephaly and reversed brain malformations in patient-derived organoids using a drug. This breakthrough may offer a treatment ...