Structure of (A) IgG; (B) pentameric IgM ... will be needed for pre-clinical and clinical testing. A panel of mammalian cell lines is suitable for the production of biopharmaceuticals [22] exist but ...

It is hard to overestimate the importance of antibodies in the frameworks of biotechnology and pharmaceutical industries.

Introducing dsRNA in somatic mammalian cells induces the antiviral interferon ... precursor RNA molecules that adopt a hairpin-and-loop structure. Similar to siRNAs, miRNAs are produced by ...

Pulsed electrical fields can be used to introduce DNA into a wide variety of animal cells 1,2. Electroporation works well with cell lines that are refractive to other techniques, such as calcium ...

More information: Zibo Chen et al, A synthetic protein-level neural network in mammalian cells, Science (2024). DOI: 10.1126/science.add8468 Katie Galloway et al, Bringing neural networks to life ...

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

Stator assigns multiple states and (sub)types to a single cell using coordinated gene expression and/or non-expression in a ...

First, circulation and blood flow to our extremities can diminish or become impaired, meaning toenails could receive fewer ...

During the development of the olfactory epithelium (OE), olfactory sensory neurons (OSNs) express only one member of the odorant receptor (OR) gene family, and O ...

Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds. The disorders ...

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein ...

W ith their hooves crunching over fallen leaves, reindeers dash into white, snowy landscapes—and folklore—as Christmas ...