The 2023 study by Nakamura and colleagues, published in Arteriosclerosis, Thrombosis, and Vascular Biology, represents a significant advancement in our understanding of aortic root aneurysm formation ...

Marfan syndrome's features were systematically described ... "The new findings could help us better understand why the aortic root is likely to dilate in patients with Loeys-Dietz syndrome ...

to compare the outcomes of aortic valve-sparing versus valve-replacing procedures in individuals with Marfan syndrome. Recruitment into the study was closed in November of 2010. The study is now in a ...

The medicines suppress progression of aneurysms in mouse models and people with Marfan syndrome, potentially reducing the risk of vascular tears, early death or the need for surgery. "The new findings ...

Transgenic mouse models of Marfan syndrome exposed a surprising and crucial function of elastic extracellular matrix components in regulating TGFβ signalling. By interacting with unprocessed ...