The 2023 study by Nakamura and colleagues, published in Arteriosclerosis, Thrombosis, and Vascular Biology, represents a significant advancement in our understanding of aortic root aneurysm formation ...

The medicines suppress progression of aneurysms in mouse models and people with Marfan syndrome, potentially reducing the risk of vascular tears, early death or the need for surgery. "The new findings ...

Marfan syndrome's features were systematically described ... "The new findings could help us better understand why the aortic root is likely to dilate in patients with Loeys-Dietz syndrome ...