Background: Medroxyprogesterone acetate (MPA), a synthetic progestogen, is extensively used for the treatment of various conditions, including contraception, irregular menstruation, functional uterine ...

Progestin-only injectable contraception with depot medroxyprogesterone acetate (DMPA) has the potential to offer top-tier efficacy because it has a first-year failure rate of only 0.3% if used ...