Factors that affect the pharmacologic effectiveness of methadone include comorbid medical disorders, pregnancy, and drug interactions. [13] The potential medical and social costs of opiate ...

Methadone is the most frequently used opioid agonist, but it is often prescribed with ambivalence and in dosages that are ineffective. Optimal dosing is influenced by many factors, including ...

Acadia Healthcare falsifies records at its methadone clinics and enrolls patients who aren’t addicted to opioids, a Times investigation found. Acadia Healthcare falsifies records at its ...

Introduction: This study systematically examines the effects of chronic oral methadone use on the glomerular filtration rate (GFR) in patients participating in methadone maintenance therapy (MMT) in ...

Researchers in 2024 made unique and important discoveries that promise to help individuals suffering from addiction and their ...

Courtesy photo Valley Vista, Vermont’s largest substance use disorder rehabilitation facility, will no longer take patients on methadone, an administrator said Thursday. The facility ...

Jan. 2, 2025 — An enzyme called MICAL2 promotes tumor growth and metastasis in the most common form of pancreatic cancer, according to a new ...

Medications like methadone and buprenorphine are recognized as the only evidence-based treatment for OUD, researchers said.

To overcome numerous health disorders, heterocyclic structures of synthetic or natural origin are utilized, and notably, the emergence of various side effects of existing drugs used for treatment or ...

Acadia Healthcare’s (ACHC) for-profit chain of 165 methadone clinics has generated more than $1.3B in revenue since 2022 and is “a business that we continue to feel great about,” Acadia’s ...

The disciplines of pharmacology and physiology touch on virtually every field of the biomedical sciences, presenting endless opportunities to discover disease mechanisms and develop new treatments.