New findings in mice have uncovered a crucial mechanism linking neuronal activity to mitochondrial function, researchers ...

Measuring mitochondrial respiration in frozen tissue samples provides the first comprehensive atlas of how aging affects mitochondrial function in mice.

Understanding mitochondrial function is essential for advancing research in cellular bioenergetics and dysfunction. However, traditional plate reader-based methods often lack the ability to measure ...

Mitochondrial DNA depletion syndrome (MTDPS ... only one deleterious variant of MICOS10 likely disrupted mitochondrial function, contributing to the patient’s condition. Functional studies ...

Mitochondrial function has been implicated in cancer for ... A large body of literature shows that mitochondrial DNA levels ...

identified a novel coupling mechanism, which they dubbed excitation-mitochondrial DNA transcription coupling ... the authors observed improved cognitive function, highlighting its potential ...

Understanding how deletion mutations in mitochondrial DNA contribute to aging can help delay age-related decline in ...

Age-related declines in mitochondrial activity are linked to sarcopenia, characterized by reduced muscle mass, strength, and function. While exercise and nutrition reduce sarcopenia, direct ...

drp-1 and fis-2 function independent of one another and the Bcl-2 homolog CED-9 and downstream of the CED-3 caspase to promote elimination of mitochondria in dying cells, an event that could ...