Bits of DNA from mitochondria can skip surprisingly fast into our genome and may reduce lifespan M ost of us remember two ...

Mitochondria are vital to energy production in cells and so play a key role in fueling cancer growth. However, how ...

New research identifies E-TCmito as a key link between neuronal activity and mitochondrial function, highlighting its ...

St. Jude researchers reveal that moderate levels of mitochondrial DNA mutations boost leukemia growth by increasing metabolic ...

Scientists have discovered a mechanism called excitation-mitochondrial DNA transcription coupling (E-TCmito) that links ...

Understanding mitochondrial function is essential for advancing research in cellular bioenergetics and dysfunction. However, traditional plate reader-based methods often lack the ability to measure ...

Within minutes of fertilization, the egg of a fruit fly becomes a scene from the battle of the sexes. The egg attacks and destroys the cellular “power plants,” or mitochondria, from the sperm that had ...

Mitochondrial DNA depletion syndrome (MTDPS ... only one deleterious variant of MICOS10 likely disrupted mitochondrial function, contributing to the patient’s condition. Functional studies ...

identified a novel coupling mechanism, which they dubbed excitation-mitochondrial DNA transcription coupling ... the authors observed improved cognitive function, highlighting its potential ...

Notably, this coupling crumbles with age in mice. Restoring it not only bolstered neuronal energy reserves, but also strengthened synaptic signaling and counteracted memory loss in old animals.

Within minutes of fertilization, the egg of a fruit fly becomes a scene from the battle of the sexes. The egg attacks and ...