Nephrotoxicity resulting from drug exposure has been estimated to contribute to 19–25% of all cases of acute kidney injury (AKI, the currently preferred term for the clinical disorder formerly ...

肾毒性机制：与其在肾皮质，尤其是近曲小管细胞中的积累有关。这些药物可损伤刷状缘膜的完整性，导致细胞内钙稳态失衡、线粒体功能障碍、增加氧化应激，最终引起细胞损伤和凋亡。在分子水平上，氨基糖苷类还能与细胞内的磷脂和蛋白质相互作用，干扰细胞的正常代谢活动。

A team developed a human iPS cell-derived kidney organoid-based proximal tubule-on-chip -- OPTECs-on-Chip -- that mimics in vivo renal physiology more closely than ever before. This model exhibits ...

Nephrotoxicity was defined in 1991 by the World Health Organization as a renal disease or dysfunction that arises as a direct or indirect result of exposure to medicines and industrial or ...

Developing advanced drug screening tools is crucial for the advancement of personalized medicine and the creation of more ...

Dates are  the dried fruits you need to help you strengthen your bones and protect your kidney. Find out more on the health ...

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Turmeric and ginger are used for many possible health benefits. Learn how this combination can be used and what research ...

Considering taking supplements to treat chemotherapy induced nephrotoxicity? Below is a list of common natural remedies used to treat or reduce the symptoms of chemotherapy induced nephrotoxicity.

Developing advanced drug screening tools is crucial for the advancement of personalized medicine and the creation of more ...

Researchers discovered that X-rays using gold nanoparticles as contrast agents may more accurately detect kidney disease.