These findings reveal a protein quality control system that operates within the nucleus for the elimination of stress-induced nucleolus-related inclusions. The cellular response to proteotoxicity ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators.

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Modern day drug discovery is shifting from single end point assays to more complex phenotypic assays that query single cell ...

The National Medical Commission (NMC) released the NEET UG 2025 syllabus, covering Physics, Chemistry, and Biology. T ...

This article was originally published with the title “ What Holds the Nucleus Together? ” in Scientific American Magazine Vol. 189 No. 3 (September 1953), p. 58 doi:10.1038 ...

LADs consist of genomic sequences with a very low transcriptional activity that is located at the periphery of the nucleus. Almost the same sequences were found to be also enriched at the periphery of ...

This innovation enables a more nuanced understanding of how drugs interact with cells, revealing insights into mechanisms beyond cell death, such as changes in the characteristics of a cell and its ...

Paul H. Guttman, M.D., Ph.D.