Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell ...

The nucleus of a cell, which contains DNA, is protected by a very selective membrane. Traditionally, accessing this area requires invasive techniques, sometimes resulting in the destruction of the ...

Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they ...

A significant discovery was the role of chromatin topology—the folding and looping of DNA within the nucleus. TFs were shown to follow DNA patterns and chromatin loops as pathways to locate target ...

The scientists take a donor egg cell, remove the nucleus (which contains the DNA), and implant a cell from the pet to be cloned. They then zap it with an electrical impulse to make the cell begin ...

In most animal, plant and fungal cells DNA is stored in the nucleus coiled up in thread-like structures called chromosomes. The nucleus of one of your skin cells contains about two metres of DNA ...

This model of the nucleus with nucleolus (pink) shows how ribosomal DNA is correctly repaired in young cells. In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to ...

Cornell researchers reveal that linker histones, previously thought to merely organize DNA, actively regulate gene expression ...

The experimental therapy Bravyl significantly reduced the spread of toxic TDP-43 protein clumps in a cell model of ALS.

Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell nuclei all at the same time ...