From combating cancer and infections to storing energy, lipid-protein interactions are critical to biological processes in ...

Novel peptide-modified lipid nanoparticles can cross the blood–brain barrier and target neurons, taking one step closer to ...

A lipid anchor on nerve cell membranes stabilizes prion proteins (PrPC) and prevents their pathological aggregation into forms linked to prion diseases.

University of Pennsylvania School of Engineering and Applied Science engineers say they have modified lipid nanoparticles (LNPs) to not only cross the blood-brain barrier (BBB) but also to target ...

"Our first paper was a proof-of-concept lipid nanoparticle design," says Michael J. Mitchell, Associate Professor in ...

Berndsen handed the data off to Keith Cassidy, another new professor, who focuses on simulation. “AlphaFold frankly can’t ...

“Our first paper was a proof-of-concept lipid nanoparticle design,” says Michael J. Mitchell, Associate Professor in Bioengineering (BE) and the paper’s senior author. “It was like showing we could ...

Testing the Concept To confirm the peptides were functioning as intended, the researchers first needed to verify they adhered to the LNPs. "Our LNPs are a complex mixture of nucleic acids, lipids ...

“Our LNPs are a complex mixture of nucleic acids, lipids and peptides,” says Han. “We had to optimize quantification methods to pick out the peptides against all those other signals.

His solution? The Triple-Lipid Peptide Cream from Skinfix. Unsolicited though it was, his advice turned out to be an absolute godsend for the rough texture I’ve struggled with every winter.