"Our first paper was a proof-of-concept lipid nanoparticle design," says Michael J. Mitchell, Associate Professor in ...

Testing the Concept To confirm the peptides were functioning as intended, the researchers first needed to verify they adhered to the LNPs. "Our LNPs are a complex mixture of nucleic acids, lipids ...

When it comes to deciding where they're going to get their next meal, different species of bees may be attracted to different ...

His solution? The Triple-Lipid Peptide Cream from Skinfix. Unsolicited though it was, his advice turned out to be an absolute godsend for the rough texture I’ve struggled with every winter.

Penn Engineers have modified lipid nanoparticles (LNPs) -; the revolutionary technology behind the COVID-19 mRNA vaccines -; to not only cross the blood-brain barrier (BBB) but also to target specific ...

Molecular self-assembly of amyloid-beta peptides to form fibrillar aggregates is a known cause of Alzheimer’s ... Cholesterol reduced the insertion of amyloid-beta into the lipid membrane, whereas ...

Structures of ApoB100 show LDL receptor contact points ...

Lipid membranes serve as the primary barrier to cell entry and the export of cellular constituents. Pathogens and cellular cargo systems have evolved proteins and peptides that mediate the cellular ...

“Our first paper was a proof-of-concept lipid nanoparticle design,” says Michael J. Mitchell, Associate Professor in Bioengineering (BE) and the paper’s senior author. “It was like showing we could ...

the research team found that the lipid chain of the fatty acid is inserted into a conserved hydrophobic pocket on the protein. Since then, Wu and his team have built a much broader chemoproteomic ...

Oat milk has come under the scanner with experts claiming it's no longer the great milk alternative we once thought it was.