Novel peptide-modified lipid nanoparticles can cross the blood–brain barrier and target neurons, taking one step closer to ...

From combating cancer and infections to storing energy, lipid-protein interactions are critical to biological processes in ...

University of Pennsylvania School of Engineering and Applied Science engineers say they have modified lipid nanoparticles (LNPs) to not only cross the blood-brain barrier (BBB) but also to target ...

A lipid anchor on nerve cell membranes stabilizes prion proteins (PrPC) and prevents their pathological aggregation into forms linked to prion diseases.

A new research perspective was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of ...

To confirm the peptides were functioning as intended, the researchers first needed to verify they adhered to the LNPs. "Our LNPs are a complex mixture of nucleic acids, lipids and peptides," says Han.