Besides forming gangliosides, sialic acid (Sia) occurs naturally at the end of sugar chains attached to the cell surface and soluble proteins. In particular, polysialic acid (polySia), a Sia polymer, ...
Therefore, this review explores the mechanisms of aberrant modifications of N-glycosylation, O-glycosylation, glycosyltransferases, and polysialic acid in the brains of SCZ patients, emphasizing their ...
Numerous medicinally relevant physiological events rely on glycoconjugates for their viability 1,2,3. The recognition of glycoprocessing enzymes as targets for therapeutic intervention has spurred ...