Skin, as the largest organ of the human body, is influenced by exposure to environmental factors such as UV radiation, which ...

According to a case–control study published in Neurology, the expression of proinflammatory cytokines is elevated in the affected skin of patients with small-fiber neuropathy (SFN).

A recent study reveals the pivotal role of tristetraprolin (TTP), an RNA-binding protein, in regulating inflammatory responses in basophils, immune cells central to allergic reactions. The research ...

Emerging evidence supports the argument that psoriatic arthritis arises from two pathways and that affected immune cells may ...

Figure 1. Cytokines involved in acute and chronic inflammatory responses (DOI:10.2741/a171). Image Credit: Sino Biological Inc. Disturbance in levels of the key pro-inflammatory cytokines ...

Tumor Necrosis Factor-alpha (TNF-α) is a cytokine important in nearly all acute inflammatory reactions by acting as an amplifier of inflammation. TNF-α blockade has been used worldwide to treat ...

T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...

Antibodies targeting IL-12/IL-23 pathways, and proinflammatory cytokines such as IFN-γ, IL-17A, IL-2 and IL-6 often showed an initial promising result, but for none of these agents efficacy has ...

That helps explain your brutal headache the next morning. But there are other chemicals at work, such as proinflammatory cytokines. These are small proteins that stimulate inflammation ...

Human cells contain two types of adenosine deaminases (ADA) each with unique properties: ADA1, which is present in all cells ...