Department of Gastroenterology and Hepatology, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands Amsterdam Gastroenterology Endocrinology Metabolism (AGEM) Research ...

Figure 1: Structures of HslVU, an ATP-dependent protease, and the DHFR substrates. The ATP-dependent proteases need to distinguish proteins that should be degraded from those that should not 4.

"Inhibiting methyltransferase required using a non-conventional RNA substrate ... there were clear advantages to looking beyond protease inhibitors. Tuschl suspected that viruses would be less ...

Scientists have has pioneered antivirals targeting viral methyltransferases, offering a new strategy for treating RNA and DNA ...

“Inhibiting methyltransferase required using a non-conventional RNA substrate adding a new challenge to drug to discovery,” Tuschl ... Tuschl realized there were clear advantages to looking beyond ...

"Inhibiting methyltransferase required using a non-conventional RNA substrate adding a new ... were clear advantages to looking beyond protease inhibitors. Tuschl suspected that viruses would ...

Define the fluorescent molecule, types of transport proteins, and expression system used in the study. 2. Identify 3 differences between radioligand binding and fluorescent substrate microplate ...

Connectase, and 0.066 eq. BcPAP. The substrate concentration was 100 μM (except for D: 10 μM) and the incubation temperature was 22°C (except for E: 10°C). In experiment F, an MBP protein with an ...