Molecular evolution is the area of evolutionary ... and changes in genome structure. Here, the authors build a map of how mutations alter the binding of JUN to all 54 human bZIP proteins ...

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Molecular Cancer Therapeutics publishes articles on the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug ...

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Using X-ray crystallography they could visualize the structure of this complex down to atomic detail, helping them to understand how the small molecule was able to recruit the two proteins together.

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Molecular Cancer Research publishes articles featuring novel, basic cancer research discoveries that prioritize broad molecular and cellular processes. Areas of emphasis include cell cycle and ...