Familial hypercholesterolemia results from gene mutations approximately halving the number of functional LDL receptors in heterozygotes and a greater lack in homozygotes. Reduced receptor-mediated ...

The epidemiology of hypercholesterolemia has been shifting in recent years. The optimal total cholesterol level is defined as about 150 mg/dL, putting low-density lipoprotein (LDL) cholesterol ...

Clin Lipidology. 2013;8(4):407-409. Homozygous familial hypercholesterolemia is a rare but significant cause of early-onset coronary heart disease. Early detection and diagnosis is crucial in at ...

Familial Hypercholesterolemia "The justly celebrated unraveling of the LDL receptor pathway revealed that mutations in a single gene give rise to familial hypercholesterolemia (FH)," Peter Libby ...

Numerous point mutations of the LDLR that result in the genetic disease familial hypercholesterolemia (FH) alter side chains that form conserved packing and hydrogen bonding interactions in the ...

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Pure mathematics uses mathematics to explore abstract ideas, mathematics that does not necessarily describe a real physical system. This can include developing the fundamental tools used by ...

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Christmas season is associated with the increased risk of hypercholesterolemia or elevated cholesterol level ... Drink water throughout the day – It is important to keep yourself well hydrated with ...

B95 Streptococcus, Staphylococcus, and Enterococcus as the cause of diseases classified elsewhere B950 Streptococcus, group A, as the cause of diseases classified elsewhere B951 Streptococcus ...