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During immune synapse formation, the microtubule organizing centre (MTOC) and the Golgi of the T cell reorient towards the APC to ensure targeted delivery of signalling molecules, such as the T ...

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Moreover, upon BCR activation using surface-bound antigen, Vti1b polarised to the immunological synapse, colocalising with the Golgi complex, and with lysosomes at actin foci. To test for a functional ...