During immune synapse formation, the microtubule organizing centre (MTOC) and the Golgi of the T cell reorient towards the APC to ensure targeted delivery of signalling molecules, such as the T ...

CAR T cell therapy revolutionizes oncology by using engineered T cells to target and eliminate cancer cells, improving ...

Upon BCR activation, Vti1b colocalised with the internalised antigen-BCR complexes and it was polarised to the immune synapse. With the hypothesis that Vti1b could play ... 10 mm HEPES and 100 U/ml ...

Your immune cells are what they eat Scientists establish novel link between cell nutrition and identity, say targeting nutrient-dependent activity could improve immunotherapies Date: December 12 ...

1 Department of Nephrology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China 2 Center for Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University ...

This study is an open-label, dose-escalation/expansion Phase I clinical trial (NCT05920876), aiming to assess the safety of ...

This case of a successful treatment of multi-refractory primary immune thrombocytopenia adds to the growing body of evidence supporting the use of CD19 CAR T-cell therapy in B cell-driven autoimmune ...

CD4 T helper cells are a type of white blood cell called a lymphocyte that serves an important role in your immune system. These cells help defend the body against infection by directing other "killer ...