The Binding Of Isaac offers lots of characters for players to use in their runs, and these are the best of them. Action: re-rolls items in a room Unlock: defeat boss Isaac with ??? Players may ...

The Binding of Isaac: Rebirth offers players a ... Players will need to beat the Isaac boss with the character ??? to unlock the D6 item. Once that's completed, Isaac will always start with ...

The latest DLC for The Binding of Isaac, Repentance, brings 8 new areas to explore, over 100 enemies as well as over 25 bosses to challenge, along with over 130 new items, new combos, and more to ...