By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...

Changes to the composition of the microbiome in neoplasia, is termed oncobiosis, may affect tumor behavior through the changes to the secretion of bacterial metabolites. In this study we show, that ...

After 48 h of treatments, cells were collected by trypsinization, washed twice with pre-cold PBS, and stained for 10 min using 10 μg/mL of Annexin V-FITC and 10 μg/mL of propidium iodide (PI) using ...