For the first time, researchers have cultivated stable tumor organoids from circulating breast cancer cells, improving ...

Tumor cells circulating in the blood are the 'germ cells' of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy ...

Table 2 shows the tissue-culture criteria for evaluation of chemotherapeutic agents on tumor cells. Here, as in the clinical study, grades were used: 0 means that no effect, 1 a questionable ...

This is a significant departure from traditional cancer treatments that rely on killing cancer cells, often leading to severe ...

Tumor cells circulating in the blood are the germ cells of breast cancer metastases. They are very rare and have not been propagated in the culture dish until now, which made research into therapy ...

Tumor cells circulating in the blood are the “germ cells” of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy ...

To address this gap, researchers analyzed gene expression within individual tumor cells. This study reports the molecular features and interactions of tumor and immune cells associated with two ...

By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...

The researchers created organoids from the tumors of patients with recurrent glioblastoma who underwent surgery as part of a Phase I clinical trial for a dual-target CAR-T cell therapy.