Ottimo Pharma Ltd. is equipped to file an IND and take its lead bifunctional antibody into phase II development, after closing a $140 million series A. The round will accelerate development of ...

This review discusses the vasculature-immunity crosstalk in the tumor microenvironment and summarizes the latest advances in combining anti-angiogenic therapy and immune checkpoint inhibitors to treat ...

Enhanced transparency and exchange of information to put an end to bank secrecy and fight tax evasion and avoidance ...

Source: Shutterstock Researchers compared the nephrotoxicity of VEGF tyrosine kinase inhibitor (TKI) therapy alone, the combination of a VEGF TKI and an immune checkpoint inhibitor (ICI), and ICI ...

and development of novel treatment strategies. Prospective pilot clinical drug trials with cannabidiol (Epidiolex) or with sirolimus, an mTOR inhibitor, indicate possible reductions in seizure ...

BioNTech obtained the candidate when it bought Biotheus last month in an acquisition deal that could reach up to $950 million. BioNTech on Tuesday revealed Phase Ib/II data for its investigational ...

Cholinesterase inhibitors prevent the breakdown of a type of neurotransmitter called acetylcholine. Doctors may prescribe this medication for certain neurodegenerative diseases, such as Alzheimer ...

Despite an improvement in near-term prospects, the global outlook remains subdued by historical standards. In 2024-25, growth is set to underperform its 2010s average in nearly 60 percent of economies ...

Low-Impact Development (LID) By managing water runoff at its source through techniques like bioswales and retention ponds, low-impact development reduces flooding risks while protecting water quality.